Jump to main content
Jump to site search

Issue 19, 2019
Previous Article Next Article

Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters

Author affiliations

Abstract

The presence of different aldehydes is found to have a significant influence on the catalytic performance when using PN(H)P type ligands for dehydrogenation of alcohols. Accordingly, hybrid multi-dentate ligands were discovered based on an oxygen-transfer alkylation of PNP ligands by aldehydes. The relevant Ru-PNN(PO) system provided the desired unsymmetrical esters in good yields via acceptorless dehydrogenation of alcohols. Hydrogen bonding interactions between the phosphine oxide moieties and alcohol substrates likely assisted the observed high chemoselectivity.

Graphical abstract: Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters

Back to tab navigation

Supplementary files

Publication details

The article was received on 31 Dec 2018, accepted on 04 Feb 2019 and first published on 05 Feb 2019


Article type: Communication
DOI: 10.1039/C8CC10315A
Citation: Chem. Commun., 2019,55, 2797-2800

  •   Request permissions

    Aldehyde effect and ligand discovery in Ru-catalyzed dehydrogenative cross-coupling of alcohols to esters

    X. Jiang, J. Zhang, D. Zhao and Y. Li, Chem. Commun., 2019, 55, 2797
    DOI: 10.1039/C8CC10315A

Search articles by author

Spotlight

Advertisements