Issue 17, 2019

A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

Abstract

A novel near-infrared fluorescent light-up probe with a tumor-homing pentapeptide, CREKA (Cys-Arg-Glu-Lys-Ala), specifically binds to fibrin–fibronectin complexes was rationally designed and developed for biomedical imaging. Its superior practical applications in tumor imaging and drug-induced liver injury detection are well demonstrated for the first time.

Graphical abstract: A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

Supplementary files

Article information

Article type
Communication
Submitted
29 Dec 2018
Accepted
30 Jan 2019
First published
30 Jan 2019

Chem. Commun., 2019,55, 2541-2544

A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

X. Zeng, Z. Chen, L. Tang, H. Yang, N. Liu, H. Zhou, Y. Li, J. Wu, Z. Deng, Y. Yu, H. Deng, X. Hong and Y. Xiao, Chem. Commun., 2019, 55, 2541 DOI: 10.1039/C8CC10286D

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