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Issue 17, 2019
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A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

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Abstract

A novel near-infrared fluorescent light-up probe with a tumor-homing pentapeptide, CREKA (Cys-Arg-Glu-Lys-Ala), specifically binds to fibrin–fibronectin complexes was rationally designed and developed for biomedical imaging. Its superior practical applications in tumor imaging and drug-induced liver injury detection are well demonstrated for the first time.

Graphical abstract: A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

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Publication details

The article was received on 29 Dec 2018, accepted on 30 Jan 2019 and first published on 30 Jan 2019


Article type: Communication
DOI: 10.1039/C8CC10286D
Citation: Chem. Commun., 2019,55, 2541-2544

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    A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection

    X. Zeng, Z. Chen, L. Tang, H. Yang, N. Liu, H. Zhou, Y. Li, J. Wu, Z. Deng, Y. Yu, H. Deng, X. Hong and Y. Xiao, Chem. Commun., 2019, 55, 2541
    DOI: 10.1039/C8CC10286D

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