Issue 33, 2019

Double-headed nanosystems for oral drug delivery

Abstract

We demonstrate a novel strategy to engineer double-headed nanosystems by chemical modification of the carboxyl terminal polyester with a linker that offers tripodal arrangement of ligands on the particle surfaces. The in vivo results suggest that the bioavailability of encapsulated curcumin is proportional to the ligand density rendered by double-headed nanosystems.

Graphical abstract: Double-headed nanosystems for oral drug delivery

Supplementary files

Article information

Article type
Communication
Submitted
18 Dec 2018
Accepted
06 Mar 2019
First published
06 Mar 2019

Chem. Commun., 2019,55, 4761-4764

Double-headed nanosystems for oral drug delivery

G. Kaur, M. Arora, R. Ganugula and M. N. V. R. Kumar, Chem. Commun., 2019, 55, 4761 DOI: 10.1039/C8CC10021G

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