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Issue 33, 2019
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Double-headed nanosystems for oral drug delivery

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Abstract

We demonstrate a novel strategy to engineer double-headed nanosystems by chemical modification of the carboxyl terminal polyester with a linker that offers tripodal arrangement of ligands on the particle surfaces. The in vivo results suggest that the bioavailability of encapsulated curcumin is proportional to the ligand density rendered by double-headed nanosystems.

Graphical abstract: Double-headed nanosystems for oral drug delivery

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Publication details

The article was received on 18 Dec 2018, accepted on 06 Mar 2019 and first published on 06 Mar 2019


Article type: Communication
DOI: 10.1039/C8CC10021G
Citation: Chem. Commun., 2019,55, 4761-4764

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    Double-headed nanosystems for oral drug delivery

    G. Kaur, M. Arora, R. Ganugula and M. N. V. R. Kumar, Chem. Commun., 2019, 55, 4761
    DOI: 10.1039/C8CC10021G

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