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Quercetin dual interaction at the membrane level

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Abstract

Quercetin impact on lipid bilayers suggests a dual action mechanism at cell membranes. This widespread polyphenol displays high partition with low interference in the more fluid membrane domains, more vulnerable to oxidative attack, but strong perturbation of cholesterol/sphingolipid enriched domains, where signalling platforms are expected to assemble.

Graphical abstract: Quercetin dual interaction at the membrane level

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Publication details

The article was received on 04 Dec 2018, accepted on 10 Jan 2019 and first published on 10 Jan 2019


Article type: Communication
DOI: 10.1039/C8CC09656B
Citation: Chem. Commun., 2019, Advance Article
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    Quercetin dual interaction at the membrane level

    A. de Granada-Flor, C. Sousa, H. A. L. Filipe, M. S. C. S. Santos and R. F. M. de Almeida, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC09656B

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