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Real-time visualizing autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

Abstract

A benzimidazole-decorated two-photon fluorescent probe (Lyso-MPCB) basing on the p-methoxyphenylacetylene-substituted carbazole was developed for detecting lysosomal pH with a double-channel signal, which can be used to visualize autophagy by real-time imaging the fluctuation of pH in lysosomes.

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Publication details

The article was received on 30 Nov 2018, accepted on 10 Jan 2019 and first published on 11 Jan 2019


Article type: Communication
DOI: 10.1039/C8CC09517E
Citation: Chem. Commun., 2019, Accepted Manuscript
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    Real-time visualizing autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

    P. Ning, L. Hou, Y. Feng, G. Xu, Y. Bai, H. Yu and X. Meng, Chem. Commun., 2019, Accepted Manuscript , DOI: 10.1039/C8CC09517E

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