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Issue 16, 2019
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Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells

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Abstract

Paclitaxel-loaded nanoparticles based on a bispillar[5]arene compound were successfully developed using a microemulsion method for the first time. The nanoparticles exhibited dual stimuli-responsiveness towards both spermine and glutathione, allowing precisely selective drug release in lung cancer cells that overexpress both stimuli.

Graphical abstract: Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells

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Publication details

The article was received on 27 Nov 2018, accepted on 29 Jan 2019 and first published on 29 Jan 2019


Article type: Communication
DOI: 10.1039/C8CC09432B
Citation: Chem. Commun., 2019,55, 2340-2343

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    Dual stimuli-responsive bispillar[5]arene-based nanoparticles for precisely selective drug delivery in cancer cells

    Q. Cheng, K. Teng, Y. Ding, L. Yue, Q. Yang and R. Wang, Chem. Commun., 2019, 55, 2340
    DOI: 10.1039/C8CC09432B

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