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A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy

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Abstract

A perylene probe PC4 is explored as a smart lysosome-targeted photosensitizer. It can efficiently kill cancer cells and also mark dead cells with bright fluorescence emission in nuclei for real-time monitoring and assessing of the photodynamic therapeutic efficiency.

Graphical abstract: A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy

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Publication details

The article was received on 26 Nov 2018, accepted on 20 Dec 2018 and first published on 21 Dec 2018


Article type: Communication
DOI: 10.1039/C8CC09396B
Citation: Chem. Commun., 2019, Advance Article
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    A smart perylene derived photosensitizer for lysosome-targeted and self-assessed photodynamic therapy

    N. Niu, H. Zhou, N. Liu, H. Jiang, E. Hussain, Z. Hu and C. Yu, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC09396B

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