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Issue 11, 2019
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A peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells

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Abstract

We develop a novel peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of tumor-related proteases in living cells. This nanoprobe responds rapidly and selectively, enabling simultaneous and high-contrast imaging of multiple proteases in living cells. Furthermore, it could detect the changes of protease expression in living cells.

Graphical abstract: A peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells

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Publication details

The article was received on 24 Nov 2018, accepted on 11 Jan 2019 and first published on 12 Jan 2019


Article type: Communication
DOI: 10.1039/C8CC09359H
Citation: Chem. Commun., 2019,55, 1651-1654

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    A peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells

    J. Xu, L. Fang, M. Shi, Y. Huang, L. Yao, S. Zhao, L. Zhang and H. Liang, Chem. Commun., 2019, 55, 1651
    DOI: 10.1039/C8CC09359H

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