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Issue 14, 2019
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Visualizing telomerase activity for tumour identification by hybridization-triggered ratiometric fluorescence

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Abstract

Telomerase is repressed stringently in normal cells but highly activated in tumours to maintain their uncontrollable growth. We report a ratiometric fluorescence strategy for visualising telomerase activity for tumour identification. Using our strategy, tumour cells and tissues can be differentiated from normal cells and tissues by the naked eye.

Graphical abstract: Visualizing telomerase activity for tumour identification by hybridization-triggered ratiometric fluorescence

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Article information


Submitted
21 Nov 2018
Accepted
14 Jan 2019
First published
14 Jan 2019

Chem. Commun., 2019,55, 2035-2038
Article type
Communication

Visualizing telomerase activity for tumour identification by hybridization-triggered ratiometric fluorescence

M. Zheng, R. Zhang, X. Tian, Z. Liu and Z. Zhang, Chem. Commun., 2019, 55, 2035
DOI: 10.1039/C8CC09257E

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