A ratiometric fluorescent probe of methionine sulfoxide reductase, Msr-Ratio, was disclosed for monitoring the enzyme activity in vitro and in live cells. The probe displayed favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large Stokes shift (120 nm), and green emission (550 nm).
L. Zhang, S. Peng, J. Sun, R. Liu, S. Liu and J. Fang, Chem. Commun., 2019, 55, 1502 DOI: 10.1039/C8CC08879A
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