Issue 7, 2019

An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

Abstract

The 5′-end thiolated aptamer is attached on the electrode surface through hybridization with immobilized assistant strands. Then the signal enhancing platform of gold nanoparticles and an electroactive Cu2+L-cysteine tag are in situ tethered on the 5′-end of the aptamer, through which, a sensitive and reusable aptasensor is facilely constructed.

Graphical abstract: An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

Supplementary files

Article information

Article type
Communication
Submitted
28 Oct 2018
Accepted
28 Nov 2018
First published
29 Nov 2018

Chem. Commun., 2019,55, 905-908

An in situ assembly strategy for the construction of a sensitive and reusable electrochemical aptasensor

J. Song, S. Li, F. Gao, Q. Wang and Z. Lin, Chem. Commun., 2019, 55, 905 DOI: 10.1039/C8CC08615J

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