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Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity

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Abstract

An activatable organic semiconducting nanoprobe that specifically turns on its second near-infrared window fluorescence upon being exposed to nitric oxide stimuli was developed for in vivo, in situ, real-time and high-spatial-resolution mapping of drug-induced hepatotoxicity.

Graphical abstract: Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity

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Publication details

The article was received on 20 Oct 2018, accepted on 13 Nov 2018 and first published on 13 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08413K
Citation: Chem. Commun., 2019, Advance Article
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    Organic semiconducting nanoprobe with redox-activatable NIR-II fluorescence for in vivo real-time monitoring of drug toxicity

    Y. Tang, Y. Li, Z. Wang, F. Pei, X. Hu, Y. Ji, X. Li, H. Zhao, W. Hu, X. Lu, Q. Fan and W. Huang, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC08413K

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