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A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

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Abstract

Atomically dispersed Fe–N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.

Graphical abstract: A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

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Publication details

The article was received on 10 Oct 2018, accepted on 19 Nov 2018 and first published on 19 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08116F
Citation: Chem. Commun., 2019, Advance Article
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    A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

    W. Ma, J. Mao, X. Yang, C. Pan, W. Chen, M. Wang, P. Yu, L. Mao and Y. Li, Chem. Commun., 2019, Advance Article , DOI: 10.1039/C8CC08116F

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