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Issue 18, 2019
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Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

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Abstract

A novel bacterial quorum quenching system is presented. For the first time the degradation of N-L-hexanoyl homoserine lactone (C6-AHL), a Gram-negative quorum sensing autoinducer, has been enhanced using molecularly imprinted nanoparticles (MIP NPs) which were prepared using transition state analogue of the γ-lactone ring hydrolysis as template.

Graphical abstract: Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

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Publication details

The article was received on 24 Sep 2018, accepted on 04 Feb 2019 and first published on 04 Feb 2019


Article type: Communication
DOI: 10.1039/C8CC07685E
Citation: Chem. Commun., 2019,55, 2664-2667

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    Application of molecularly imprinted polymer nanoparticles for degradation of the bacterial autoinducer N-hexanoyl homoserine lactone

    J. Garcia Lopez, E. V. Piletska, M. J. Whitcombe, J. Czulak and S. A. Piletsky, Chem. Commun., 2019, 55, 2664
    DOI: 10.1039/C8CC07685E

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