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Advances in biomolecule inspired polymeric material decorated interfaces for biological applications

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Abstract

With the development of surface modification technology, interface properties have great effects on the interaction between biomedical materials and cells and biomolecules, which significantly affects the biocompatibility and functionality of materials. As an orderly and perfect system, biological organisms in nature effectively integrate all kinds of bio-interfaces with physiological functions, which shed light on the importance of biomolecules in organisms. It gives birth to a bio-inspiration strategy to design and fabricate smart materials with specific functionalities, e.g. osteogenic and chondrocytic induced materials inspired by bone sialoprotein and chondroitin sulfate. Through this mimicking approach, various functional materials were utilized to decorate the interfaces and further optimize the performance of biomedical materials, which would widely expand their applications. In this review, followed by a summary and brief introduction of surface modification methods, we highlight recent advances in the fabrication of functional polymeric materials inspired by a range of biomolecules for decorating interfaces. Then, the other applications of biomolecule inspired materials including tissue engineering, diagnosis and treatment of diseases and physiological function regulation are presented and the future outlook is discussed as well.

Graphical abstract: Advances in biomolecule inspired polymeric material decorated interfaces for biological applications

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Publication details

The article was received on 14 May 2019, accepted on 08 Aug 2019 and first published on 09 Aug 2019


Article type: Review Article
DOI: 10.1039/C9BM00746F
Biomater. Sci., 2019, Advance Article

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    Advances in biomolecule inspired polymeric material decorated interfaces for biological applications

    D. Zhang, X. Xu, X. Long, K. Cheng and J. Li, Biomater. Sci., 2019, Advance Article , DOI: 10.1039/C9BM00746F

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