Jump to main content
Jump to site search


Microneedles combined with a sticky and heatable hydrogel for local painless anesthesia

Author affiliations

Abstract

In view of the inherent defects of traditional syringe anesthesia (pain, inaccurate anesthesia area, swelling after injection, slow recovery etc.), this article proposed a new anesthesia system based on microneedles and a hydrogel. After loading with AuNPs, a sticky PDA-PAM-AuNP hydrogel with near-infrared (NIR) light response properties was prepared here. After using microneedles (to open the skin of the target anesthesia area), a hydrogel patch embedded with a medical anesthetic soaked sponge was pasted to realize local painless anesthesia. The effects of anesthesia can also be modulated by external NIR. Compared to traditional syringe anesthesia, this hydrogel + microneedle method resulted in reduced pain, higher anesthetic accuracy and faster recovery, making it a promising local anesthesia alternative in clinical applications.

Graphical abstract: Microneedles combined with a sticky and heatable hydrogel for local painless anesthesia

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Mar 2019, accepted on 17 Sep 2019 and first published on 18 Sep 2019


Article type: Communication
DOI: 10.1039/C9BM00482C
Biomater. Sci., 2019, Advance Article

  •   Request permissions

    Microneedles combined with a sticky and heatable hydrogel for local painless anesthesia

    F. Zhang, W. Bao, R. Li, S. Zhao, Y. Liu, Y. Xu, L. Liao and X. Wang, Biomater. Sci., 2019, Advance Article , DOI: 10.1039/C9BM00482C

Search articles by author

Spotlight

Advertisements