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Issue 9, 2019
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Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

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Abstract

Detection of the biofilm of bacteria would be a counter strategy to detect hidden bacteria in their camouflage. Through unbiased screening of bacteria biofilm, we discovered a long wavelength probe CDr15 with extracellular DNA as the molecular target. CDr15 revealed a real-time geometric distribution of eDNA in a 3D bacterial colony.

Graphical abstract: Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

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Article information


Submitted
30 Jan 2019
Accepted
02 Jul 2019
First published
22 Jul 2019

Biomater. Sci., 2019,7, 3594-3598
Article type
Communication

Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

H. Kwon, J. Kim, X. Liu, J. Y. Lee, J. K. H. Yam, L. Dahl Hultqvist, W. Xu, M. Rybtke, T. Tolker-Nielsen, W. Heo, J. Kim, N. Kang, T. Joo, L. Yang, S. Park, M. Givskov and Y. Chang, Biomater. Sci., 2019, 7, 3594
DOI: 10.1039/C9BM00152B

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