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Advances in crosslinking strategies of biomedical hydrogels

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Abstract

Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and bioactive growth factors are extensively applied in tissue engineering and regenerative medicine. Hydrogels normally provide three dimensional structures for cell adhesion and proliferation or the controlled release of the loading of drugs or proteins. Various physiochemical properties of hydrogels endow them with distinct applications. In this review, we present the commonly used crosslinking method for hydrogel synthesis involving physical and chemical crosslinks and summarize their current progress and future perspectives.

Graphical abstract: Advances in crosslinking strategies of biomedical hydrogels

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Publication details

The article was received on 06 Oct 2018, accepted on 24 Dec 2018 and first published on 26 Dec 2018


Article type: Minireview
DOI: 10.1039/C8BM01246F
Citation: Biomater. Sci., 2019, Advance Article
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    Advances in crosslinking strategies of biomedical hydrogels

    W. Hu, Z. Wang, Y. Xiao, S. Zhang and J. Wang, Biomater. Sci., 2019, Advance Article , DOI: 10.1039/C8BM01246F

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