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A mitochondria–nucleolus migration fluorescent probe for monitoring of mitochondrial membrane potential and identification of cell apoptosis

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Abstract

A dicationic probe (Cz-Bz-1) was presented with excellent photostability and large Stokes shifts, which could migrate from mitochondria to the nucleolus and report mitochondrial membrane potential (MMP) changes. Moreover, Cz-Bz-1 was successfully applied to visualize the decrease of MMP induced by H2O2 and cis-platinum during cell apoptosis.

Graphical abstract: A mitochondria–nucleolus migration fluorescent probe for monitoring of mitochondrial membrane potential and identification of cell apoptosis

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Publication details

The article was received on 25 Aug 2019, accepted on 23 Oct 2019 and first published on 24 Oct 2019


Article type: Communication
DOI: 10.1039/C9AY01836K
Anal. Methods, 2019, Advance Article

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    A mitochondria–nucleolus migration fluorescent probe for monitoring of mitochondrial membrane potential and identification of cell apoptosis

    M. Li, Y. Liu, K. Li, H. Zhang, L. Shi, X. Liu, K. Yu and X. Yu, Anal. Methods, 2019, Advance Article , DOI: 10.1039/C9AY01836K

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