Issue 1, 2020

An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

Abstract

This study presents a rapid, simple, sensitive, and selective electrochemical sensor prepared using a carbon paste electrode for the electrochemical determination of buserelin—an anti-prostate cancer drug. Differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques were applied to analyze the anodic characterization of the aforementioned drug. Some of the common parameters such as pH, scan rate, and sensitivity have been studied by using the aforementioned electrochemical techniques. The DPV technique showed a remarkable linearity in the concentration range of 1.0 × 10−4 to 6.0 × 10−6 μM with a limit of detection of 0.73 μM. Moreover, the present study could be successfully applied for the determination of buserelin in human serum samples.

Graphical abstract: An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

Article information

Article type
Paper
Submitted
16 Aug 2019
Accepted
10 Nov 2019
First published
19 Nov 2019

Anal. Methods, 2020,12, 33-38

An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

M. Fallah, M. Rahimnejad, M. Asghary and M. Mashkour, Anal. Methods, 2020, 12, 33 DOI: 10.1039/C9AY01760G

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