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An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

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Abstract

This study presents a rapid, simple, sensitive, and selective electrochemical sensor prepared using a carbon paste electrode for the electrochemical determination of buserelin—an anti-prostate cancer drug. Differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques were applied to analyze the anodic characterization of the aforementioned drug. Some of the common parameters such as pH, scan rate, and sensitivity have been studied by using the aforementioned electrochemical techniques. The DPV technique showed a remarkable linearity in the concentration range of 1.0 × 10−4 to 6.0 × 10−6 μM with a limit of detection of 0.73 μM. Moreover, the present study could be successfully applied for the determination of buserelin in human serum samples.

Graphical abstract: An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

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Publication details

The article was received on 16 Aug 2019, accepted on 10 Nov 2019 and first published on 19 Nov 2019


Article type: Paper
DOI: 10.1039/C9AY01760G
Anal. Methods, 2020, Advance Article

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    An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

    M. Fallah, M. Rahimnejad, M. Asghary and M. Mashkour, Anal. Methods, 2020, Advance Article , DOI: 10.1039/C9AY01760G

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