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Issue 33, 2019
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Multi-approach cysteine detection based on supramolecular transformation induced by G-quadruplexes

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Abstract

Development of a cysteine (Cys) detection probe is of significant importance in clinical diagnosis. Herein, a colorimetric, chiral and fluorometric multi-approach detection probe for Cys has been designed. This probe utilized G-quadruplexes as a template to regulate the supramolecular transformation of a cyanine dye and achieve label-free and highly selective detection of Cys. Its successful use in urinary Cys measurement demonstrates good promise for practical applications.

Graphical abstract: Multi-approach cysteine detection based on supramolecular transformation induced by G-quadruplexes

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Publication details

The article was received on 24 Jun 2019, accepted on 22 Jul 2019 and first published on 23 Jul 2019


Article type: Paper
DOI: 10.1039/C9AY01323G
Anal. Methods, 2019,11, 4249-4253

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    Multi-approach cysteine detection based on supramolecular transformation induced by G-quadruplexes

    D. Yang, H. Chen, Q. Li, X. Zhang, H. Sun and Y. Tang, Anal. Methods, 2019, 11, 4249
    DOI: 10.1039/C9AY01323G

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