Jump to main content
Jump to site search


A Novel NBD-based Fluorescent Turn-on Probe for Detection of Phosgene in Solutions and the Gas Phase

Abstract

As a highly toxic gas, phosgene (COCl2) is widely used in chemical industry processes. Because of its colorlessness and acute effects, the detection of phosgene is important for public health safety. In this work, we reported a novel 7-nitro-2,1,3-benzoxadiazole(NBD)-based fluorescent probe. It is constructed with 1,4,7-triazacyclononane moiety as the active site, which includes two aliphatic secondary amines and one aromatic tertiary amine. The 1- nitrogen atom connected to aromatic ring facilitates the intramolecular charge transfer (ICT) process, providing high quality of fluorescence potential. The 4- and 7- nitrogen atoms are used as double-sites recognition group and also as effective photoinduced electron transfer (PET) donors. The NBD-1,4,7-triazacyclonenane probe can be bis-carbamylated with phosgene to block the PET effects, which give a turn-on fluorescent response at 525 nm. The sensing reaction can be achieved within 20 s in solutions. The probe's response to triphosgene is highly sensitive and selective, and the detection limit is as low as 1.2 nM to triphosgene in solutions. Furthermore, a portable filter paper has been produced for real-time detection of phosgene in the gas phase.

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Jun 2019, accepted on 05 Aug 2019 and first published on 05 Aug 2019


Article type: Paper
DOI: 10.1039/C9AY01285K
Anal. Methods, 2019, Accepted Manuscript

  •   Request permissions

    A Novel NBD-based Fluorescent Turn-on Probe for Detection of Phosgene in Solutions and the Gas Phase

    L. Yang, Z. Sun, Z. Li, X. Kong, F. Wang, X. Liu, J. Tang, M. Ping and J. You, Anal. Methods, 2019, Accepted Manuscript , DOI: 10.1039/C9AY01285K

Search articles by author

Spotlight

Advertisements