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Issue 40, 2019
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A disposable acetylcholine esterase sensor for As(iii) determination in groundwater matrix based on 4-acetoxyphenol hydrolysis

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Abstract

There is a lack of field compatible analytical methods for the speciation of As(III) to characterize groundwater pollution at anthropogenic sites. To address this issue, an inhibition-based acetylcholine esterase (AchE) sensor was developed to determine As(III) in groundwater. 4-Acetoxyphenol was employed to develop an amperometric assay for AchE activity. This assay was used to guide the fabrication of an AchE sensor with screen-printed carbon electrode. An As(III) determination protocol was developed based on the pseudo-irreversible inhibition mechanism. The analysis has a dynamic range of 2–500 μM (150–37 500 μg L−1) for As(III). The sensor exhibited the same dynamic range and sensitivity in a synthetic groundwater matrix. The electrode was stable for at least 150 days at 22 ± 2 °C.

Graphical abstract: A disposable acetylcholine esterase sensor for As(iii) determination in groundwater matrix based on 4-acetoxyphenol hydrolysis

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Publication details

The article was received on 06 Jun 2019, accepted on 26 Sep 2019 and first published on 26 Sep 2019


Article type: Paper
DOI: 10.1039/C9AY01199D
Anal. Methods, 2019,11, 5203-5213

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    A disposable acetylcholine esterase sensor for As(III) determination in groundwater matrix based on 4-acetoxyphenol hydrolysis

    T. Li, J. Berberich, E. Sahle-Demessie and E. Varughese, Anal. Methods, 2019, 11, 5203
    DOI: 10.1039/C9AY01199D

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