Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction

Dan Sun; Weiqing Xu; Shuping Xu

doi:10.1039/C9AY01033E

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Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction†

Dan Sun,^a Weiqing Xu

^a and Shuping Xu

*^a

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* Corresponding authors

^a State Key Laboratory of Supramolecular Structure and Materials, Institute of Theoretical Chemistry, College of Chemistry, Jilin University, Changchun 130012, PR China
E-mail: xusp@jlu.edu.cn

Abstract

A simple and highly sensitive Raman approach for detecting alkaline phosphatase (ALP) is developed on the basis of the conversion of fosfosal to salicylic acid via an ALP-catalyzed reaction. This method can be used for the clinical detection of ALP in serum.

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DOI: https://doi.org/10.1039/C9AY01033E
Article type: Communication
Submitted: 17 May 2019
Accepted: 13 Jun 2019
First published: 17 Jun 2019

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Anal. Methods, 2019,11, 3501-3505

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Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction

D. Sun, W. Xu and S. Xu, Anal. Methods, 2019, 11, 3501 DOI: 10.1039/C9AY01033E

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Analytical Methods

Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction†

Abstract

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Ultrasensitive Raman sensing of alkaline phosphatase activity in serum based on an enzyme-catalyzed reaction

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