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Issue 22, 2019
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Fabrication of an antibiotic-sensitive 2D-molecularly imprinted photonic crystal

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Abstract

A molecularly imprinted colloidal array (MICA) for the detection of clindamycin hydrochloride (CLI) was prepared by embedding a two-dimensional (2D) polystyrene crystalline colloidal array within a CLI-imprinted hydrogel. The MICA showed a significant response to CLI, in which the particle spacing of the MICA changed 41 nm within 10 min in response to 1 mM CLI, and the structural color of the MICA changed from blue, green, to yellow, and finally, to red. Furthermore, MICA was also used to detect a similar antibiotic, lincomycin, which had only induced a 10 nm change in the spacing. The MICA was reused more than 5 times. This low-cost and naked-eye sensing material provides a label-free way to detect CLI and other antibiotics.

Graphical abstract: Fabrication of an antibiotic-sensitive 2D-molecularly imprinted photonic crystal

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Article information


Submitted
01 Apr 2019
Accepted
05 May 2019
First published
06 May 2019

Anal. Methods, 2019,11, 2875-2879
Article type
Paper

Fabrication of an antibiotic-sensitive 2D-molecularly imprinted photonic crystal

Y. Wang, J. Fan, Z. Meng, M. Xue and L. Qiu, Anal. Methods, 2019, 11, 2875
DOI: 10.1039/C9AY00674E

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