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A Rhodamine-Based Fluorescent Probe for Fe3+: Synthesis, Theoretical Calculation and Bioimaging Application

Abstract

A novel rhodamine-based fluorescent probe was designed and synthesized. Selection on metal ions illuminated the highly specific recognition of probe towards Fe3+ over other metal ions, meanwhile, the color change in the recognition process of Fe3+ could be used for its “naked-eye” detection in aqueous environment. And a theoretical calculation was performed to reveal the possible reaction mechanism between the probe and Fe3+. Fluorescent imaging of Fe3+ in living cells furtherly suggested future applications of the probe for instant Fe3+ detection in clinical diagnosis and dynamic tracking of Fe3+ in biological systems.

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Publication details

The article was received on 10 Mar 2019, accepted on 10 Apr 2019 and first published on 12 Apr 2019


Article type: Paper
DOI: 10.1039/C9AY00499H
Citation: Anal. Methods, 2019, Accepted Manuscript

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    A Rhodamine-Based Fluorescent Probe for Fe3+: Synthesis, Theoretical Calculation and Bioimaging Application

    Z. Cheng, L. Zheng, H. Xu, L. Pang and H. He, Anal. Methods, 2019, Accepted Manuscript , DOI: 10.1039/C9AY00499H

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