Micellar catalysis of an Iron (III)-MOF: Enhanced Biosensing Characteristics
Recent years have seen an enormous growth of interest in enzyme mimics based on porous materials as a substitute of the natural enzyme. This interest has been motivated to a considerable extent due to this fact that they have outstanding chemical and structural features. Herein, Zr6O8(H2O)8(FeCl-tcpp)2 (PCN-222(Fe)) was synthesized via a solvothermal approach from Zr6 clusters as nodes and Fe-TCPP (TCPP=tetrakis(4carboxyphenyl)porphyrin) as a heme-like ligand and were characterized by various techniques such as XRD, TEM, SEM, XPS, UV-Vis and IR. Also, since the achievement of high enzyme-like activity of some nanoparticles has attracted a widespread concern in recent years, for the first time, we have applied a significant approach by modifying PCN-222(Fe) with sodium dodecyl sulfate (SDS) micelles (SDS/PCN-222(Fe)). In an attempt to explore the significance of this procedure, initially, peroxidase and catalase-like activity were investigated through a reaction with chromogenic substrate 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS). Based on the high peroxidatic activity of SDS/PCN-222(Fe) , the visual, sensitive and reliable method was established for detection of H2O2 with a linear range of 3–200 μM and limit of detection (LOD) of 2 μM. Also, with an implication of these findings, the SDS/ Zr6O8(H2O)8(FeCl-tcpp)2 (SDS/PCN-222(Fe)) based system could also be used for glucose assay with a LOD of 3 μM indicating potential applications in clinical medicine. In order to prove this hypothesis, the glucose detection in human serum was determined. Finally, on this basis of SDS/PCN-222(Fe) performance, three natural antioxidants, gallic acid (GA), tannic acid (TA), and ascorbic acid (AA) were applied to explore antioxidant capabilities.