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Issue 10, 2019
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A rapid and highly selective paper-based device for high-throughput detection of cysteine with red fluorescence emission and a large Stokes shift

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Abstract

A paper-based device is a promising technology for point-of-care testing (POCT). In this work, a novel fluorescent probe with red emission (650 nm) and a large Stokes shift (∼170 nm) for Cys detection was reported for the first time. This probe exhibited a highly selective and rapid response to Cys within 5 min. Importantly, by introducing this probe into microfluidic paper-based analytical devices (μPADs), a paper-based device was developed for simple, high-throughput and highly sensitive detection of Cys. Finally, satisfactory performance of this paper-based device for Cys detection was achieved in real samples, which indicates the great potential of our strategy in the construction of POCT systems for detecting analytes.

Graphical abstract: A rapid and highly selective paper-based device for high-throughput detection of cysteine with red fluorescence emission and a large Stokes shift

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Publication details

The article was received on 07 Jan 2019, accepted on 23 Jan 2019 and first published on 24 Jan 2019


Article type: Paper
DOI: 10.1039/C9AY00041K
Citation: Anal. Methods, 2019,11, 1312-1316

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    A rapid and highly selective paper-based device for high-throughput detection of cysteine with red fluorescence emission and a large Stokes shift

    J. Zhou, C. Yu, Z. Li, P. Peng, D. Zhang, X. Han, H. Tang, Q. Wu, L. Li and W. Huang, Anal. Methods, 2019, 11, 1312
    DOI: 10.1039/C9AY00041K

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