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Issue 13, 2019
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Monitoring the trans-membrane transport of single fluorescent silicon nanoparticles based on the force tracing technique

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Abstract

Fluorescent silicon nanoparticles (SiNPs) have been proven to be promising materials for diagnosis and therapy of diseases. As the drug carriers and markers in imaging, fluorescent SiNPs trans-membrane is the first step. However, the details of the trans-membrane transport mechanism of SiNPs are still unclear. Herein, we aim to investigate the dynamic trans-membrane transport process of single SiNPs in normal cells (Vero) and cancer cells (HeLa) by utilizing the force tracing technique based on atomic force microscopy.

Graphical abstract: Monitoring the trans-membrane transport of single fluorescent silicon nanoparticles based on the force tracing technique

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Article information


Submitted
06 Jan 2019
Accepted
07 Mar 2019
First published
07 Mar 2019

Anal. Methods, 2019,11, 1724-1728
Article type
Communication

Monitoring the trans-membrane transport of single fluorescent silicon nanoparticles based on the force tracing technique

R. Wang, X. Yang, D. Leng, Q. Zhang, D. Lu, S. Zhou, Y. Yang, G. Yang and Y. Shan, Anal. Methods, 2019, 11, 1724
DOI: 10.1039/C9AY00037B

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