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A 6-acetyl-2-naphthol based two-photon fluorescent probe for the selective detection of nitroxyl and imaging in living cells

Abstract

A novel two-photon HNO fluorescent probe (TP-HNO) was easily constructed and prepared by conbining 6-acetyl-2-naphthol and 2-(diphenylphosphino)-benzoate. TP-HNO exhibted high selectivity (more than 140-fold off-on fluorescent response) and high sensitivity (the detection limit is 78 nM) to HNO in solution. TP-HNO was also applied for two-photon imaging of HNO in living cells and in tissues.

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Publication details

The article was received on 27 Dec 2018, accepted on 11 Feb 2019 and first published on 12 Feb 2019


Article type: Communication
DOI: 10.1039/C8AY02819B
Citation: Anal. Methods, 2019, Accepted Manuscript

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    A 6-acetyl-2-naphthol based two-photon fluorescent probe for the selective detection of nitroxyl and imaging in living cells

    P. Zhang, P. Lian, X. Wang, X. Li, C. Wei and X. Li, Anal. Methods, 2019, Accepted Manuscript , DOI: 10.1039/C8AY02819B

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