Spontaneous reduction of KMnO4 with MoS2 quantum dots for glutathione sensing in tumor
Transition-metal dichalcogenides (TMDC) have attracted a lot of attention due to their electronic, optical, mechanical, and catalytic properties. Besides, the rich redox chemistry enabled their decoration on metal nanoparticles directly. In this paper, MnO2/MoS2 nanocomplex were obtained by a spontaneous reduction of KMnO4 with MoS2 QDs as the reductive agent. The formed MnO2/MoS2 nanocomplex presented an activated fluorescence and MR imaging signal to glutathione (GSH). After conjugated with AS1411 aptamer, the specific in vivo MR imaging and fluorescence labeling of 786-O tumor cells were realized, showing their promising potential for biomedial applications.