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Spontaneous reduction of KMnO4 with MoS2 quantum dots for glutathione sensing in tumor

Abstract

Transition-metal dichalcogenides (TMDC) have attracted a lot of attention due to their electronic, optical, mechanical, and catalytic properties. Besides, the rich redox chemistry enabled their decoration on metal nanoparticles directly. In this paper, MnO2/MoS2 nanocomplex were obtained by a spontaneous reduction of KMnO4 with MoS2 QDs as the reductive agent. The formed MnO2/MoS2 nanocomplex presented an activated fluorescence and MR imaging signal to glutathione (GSH). After conjugated with AS1411 aptamer, the specific in vivo MR imaging and fluorescence labeling of 786-O tumor cells were realized, showing their promising potential for biomedial applications.

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Publication details

The article was received on 08 Nov 2019, accepted on 28 Nov 2019 and first published on 28 Nov 2019


Article type: Paper
DOI: 10.1039/C9AN02239B
Analyst, 2019, Accepted Manuscript

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    Spontaneous reduction of KMnO4 with MoS2 quantum dots for glutathione sensing in tumor

    Y. Wang, L. Cai, Q. Wang, M. Zhao, L. Dong, K. Xu and J. Li, Analyst, 2019, Accepted Manuscript , DOI: 10.1039/C9AN02239B

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