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Issue 24, 2019
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Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules

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Abstract

Here, we designed and developed a Universal Baby Spinach-based Probe (UBSP) for biomolecule detection by introducing a DNA repressor containing a target recognition element. By employing different interaction modes between targets and repressors, we applied the UBSP to detect diverse classes of analytes, including microRNA, proteins, and heavy metal ions.

Graphical abstract: Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules

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Article information


Submitted
15 Oct 2019
Accepted
08 Nov 2019
First published
21 Nov 2019

Analyst, 2019,144, 7173-7177
Article type
Communication

Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules

D. Ji, Z. Li and C. K. Kwok, Analyst, 2019, 144, 7173
DOI: 10.1039/C9AN02061F

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