Jump to main content
Jump to site search


The construction of DNAzyme-based logic gates for amplified microRNA detection and cancer recognition

Author affiliations

Abstract

Benefiting from the simple DNAzyme and a duplex-specific nuclease, a series of microRNA-stimulated DNAzyme logic gates were rationally assembled for the highly accurate detection of multiple low-abundant microRNA biomarkers that correspond to the specific aberrant microRNA expression patterns of cancer tissues, thus showing a great potential in early diagnosis.

Graphical abstract: The construction of DNAzyme-based logic gates for amplified microRNA detection and cancer recognition

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 Oct 2019, accepted on 21 Oct 2019 and first published on 29 Oct 2019


Article type: Paper
DOI: 10.1039/C9AN01977D
Analyst, 2019, Advance Article

  •   Request permissions

    The construction of DNAzyme-based logic gates for amplified microRNA detection and cancer recognition

    L. Wu, M. Pan, Y. Chen, H. Huang, X. Zhang, F. Wang and X. Zhou, Analyst, 2019, Advance Article , DOI: 10.1039/C9AN01977D

Search articles by author

Spotlight

Advertisements