Jump to main content
Jump to site search


Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence

Author affiliations

Abstract

Recently, the photothermal effect of nanomaterials has opened the door for new appealing strategy, which can generate a promising and powerful tool when combined with immunoassay. As a new kind of nanomaterial, black phosphorus (BP) has aroused widespread interest. In this study, a novel immunofiltration strip method with temperature as the readout signal based on the photothermal effect of BP nanosheets was established. The temperature was monitored by a portable temperature sensor. Using an indirect competitive strategy, it provides a simple, rapid, sensitive, and economic platform for the detection of 17β-estradiol, a kind of endocrine disrupting compound that is frequently detected in environmental water or food samples. The higher the concentration of 17β-estradiol in the sample, the less BP nanosheets are brought to bind to the strip surface, along with lower temperature variation when exposed to intensive laser irradiation. Under optimum conditions, a detection limit of 0.104 ng mL−1 was achieved. The feasibility of this assay was assessed by a standard addition method in water and milk samples, showing good performance and indicating potential application value for easy-to-use, inexpensive, and on-site monitoring of 17β-estradiol.

Graphical abstract: Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Aug 2019, accepted on 16 Sep 2019 and first published on 27 Sep 2019


Article type: Paper
DOI: 10.1039/C9AN01495K
Analyst, 2019, Advance Article

  •   Request permissions

    Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence

    L. Lu, M. Wang, D. Zhang and H. Zhang, Analyst, 2019, Advance Article , DOI: 10.1039/C9AN01495K

Search articles by author

Spotlight

Advertisements