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Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

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Abstract

Despite its crucial role, the placenta is the least understood human organ. Recent clinical studies indicate a direct association between placental calcification and maternal and offspring health. This study reveals distinct characteristics of minerals formed during gestational ageing using cutting-edge nano-analytical characterization and paves the way for investigations focused on the identification of potential markers for disease risks in a clinical setting based on atypical placental mineral fingerprints.

Graphical abstract: Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

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Publication details

The article was received on 12 Jul 2019, accepted on 30 Sep 2019 and first published on 02 Oct 2019


Article type: Communication
DOI: 10.1039/C9AN01312A
Analyst, 2019, Advance Article

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    Nano-analytical characterization of endogenous minerals in healthy placental tissue: mineral distribution, composition and ultrastructure

    A. H. C. Anthis, E. Tsolaki, L. Didierlaurent, S. Staubli, R. Zboray, A. Neels, D. Dietrich, P. Manser, L. M. Desbiolles, S. Leschka, S. Wildermuth, S. Lehner, P. Chavatte-Palmer, W. Jochum, P. Wick, A. Dommann, T. Bürki-Turnherr, T. Fischer, R. Hornung, S. Bertazzo and I. K. Herrmann, Analyst, 2019, Advance Article , DOI: 10.1039/C9AN01312A

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