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Facile synthesis of metal–organic framework-derived SiW12@Co3O4 and its peroxidase-like activity in colorimetric assay

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Abstract

Over the past few years, artificial enzymes have attracted enormous attention due to their high stabilities and cost-effective productions. In this work, metal–organic framework-derived SiW12@Co3O4 was synthesized in large quantities by stirring the mixture at ambient temperature and calcination. The obtained SiW12@Co3O4 exhibited a highly inherent peroxidase-like activity and excellent stability. Kinetic studies demonstrated that the synthesized SiW12@Co3O4 had a strong binding affinity to 3,3′,5,5′-tetramethylbenzidine (TMB), stronger than HRP had. Specifically, the peroxidase-like activity of SiW12@Co3O4 in an aqueous solution was well maintained after incubation at an elevated temperature, at an extreme pH and for a long time. A SiW12@Co3O4-based method was further developed for H2O2 and one-pot glucose detection with good sensitivity and reliability. The facile synthesis approach is expected to facilitate the practical use of metal–organic frameworks and their derivatives as enzyme mimics in the future.

Graphical abstract: Facile synthesis of metal–organic framework-derived SiW12@Co3O4 and its peroxidase-like activity in colorimetric assay

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Publication details

The article was received on 06 Jul 2019, accepted on 01 Aug 2019 and first published on 01 Aug 2019


Article type: Paper
DOI: 10.1039/C9AN01262A
Analyst, 2019, Advance Article

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    Facile synthesis of metal–organic framework-derived SiW12@Co3O4 and its peroxidase-like activity in colorimetric assay

    W. Shi, S. E, M. Wang, T. Li, T. Yang, S. Liu, M. Chen and J. Wang, Analyst, 2019, Advance Article , DOI: 10.1039/C9AN01262A

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