A new visual immunoassay for prostate-specific antigen using near-infrared excited CuxS nanocrystals and imaging on a smartphone

Shuzhen Lv; Kangyao Zhang; Dianping Tang

doi:10.1039/C9AN00724E

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A new visual immunoassay for prostate-specific antigen using near-infrared excited Cu_xS nanocrystals and imaging on a smartphone†

Shuzhen Lv,^a Kangyao Zhang^a and Dianping Tang

*^a

Author affiliations

* Corresponding authors

^a Key Laboratory for Analytical Science of Food Safety and Biology (MOE & Fujian Province), State Key Laboratory of Photocatalysis on Energy and Environment, Department of Chemistry, Fuzhou University, Fuzhou 350116, P. R. China
E-mail: dianping.tang@fzu.edu.cn
Fax: +86 591 2286 6135
Tel: +86 591 2286 6125

Abstract

A photothermal immune-imaging assay was innovatively designed for the visual quantitative detection of cancer biomarkers by coupling Cu_xS nanocrystals with a portable infrared thermal imager on a smartphone. The rolling circle amplification (RCA) technique was used for the formation of a Cu_xS nanocrystal concatemer, thus opening up new territories in immunoassay development.

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Article information

DOI: https://doi.org/10.1039/C9AN00724E
Article type: Communication
Submitted: 22 Apr 2019
Accepted: 10 May 2019
First published: 13 May 2019

Download Citation

Analyst, 2019,144, 3716-3720

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A new visual immunoassay for prostate-specific antigen using near-infrared excited Cu_xS nanocrystals and imaging on a smartphone

S. Lv, K. Zhang and D. Tang, Analyst, 2019, 144, 3716 DOI: 10.1039/C9AN00724E

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