Issue 15, 2019
From the journal:

Analyst

High-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cells

Jan Rüger,a   Abdullah Saif Mondol,ab   Iwan W. Schie, ORCID logo *ab   Jürgen Poppab  and  Christoph Krafft ORCID logo *a  

* Corresponding authors

a Leibniz Institute of Photonic Technology, Member of Leibniz Health Technologies, Albert-Einstein-Straße 9, 07745 Jena, Germany
E-mail: christoph.krafft@leibniz-ipht.de, iwan.schie@leibniz-ipht.de

b Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany

Abstract

High-throughput screening Raman spectroscopy (HTS-RS) with automated localization algorithms offers unsurpassed speed and sensitivity to investigate the effect of dithiothreitol on the diatom Phaedactylum tricornutum. The HTS-RS capability that was demonstrated for this model system can be transferred to unmet analytical applications such as kinetic in vivo studies of microalgal assemblages.

Graphical abstract: High-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cells

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Article information

DOI
https://doi.org/10.1039/C9AN00107G
Article type
Communication
Submitted
16 Jan 2019
Accepted
22 Jun 2019
First published
09 Jul 2019
This article is Open Access
Creative Commons BY-NC license

Analyst, 2019,144, 4488-4492

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High-throughput screening Raman microspectroscopy for assessment of drug-induced changes in diatom cells

J. Rüger, A. S. Mondol, I. W. Schie, J. Popp and C. Krafft, Analyst, 2019, 144, 4488 DOI: 10.1039/C9AN00107G

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