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Issue 9, 2019
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Electroanalytical identification of 25I-NBOH and 2C-I via differential pulse voltammetry: a rapid and sensitive screening method to avoid misidentification

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Abstract

25I-NBOH is a new potent serotonin 5-HT2A receptor agonist recently identified in blotter paper seizures. This compound is a thermolabile molecule that undergoes degradation under routine gas chromatography–mass spectrometry analysis leading to misidentification. In this paper, the voltammetric behavior of 25I-NBOH and 2C-I was investigated and their electroanalytical characteristics were determined. A novel, fast and sensitive electrochemical method for the detection of 25I-NBOH using a SPCE is described and all method characteristics demonstrated the method to be analytically valuable. This method is selective and achieves full differentiation between 25I-NBOH, 2C-I and 25I-NBOMe.

Graphical abstract: Electroanalytical identification of 25I-NBOH and 2C-I via differential pulse voltammetry: a rapid and sensitive screening method to avoid misidentification

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Publication details

The article was received on 10 Jan 2019, accepted on 18 Feb 2019 and first published on 20 Feb 2019


Article type: Paper
DOI: 10.1039/C9AN00062C
Citation: Analyst, 2019,144, 2965-2972

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    Electroanalytical identification of 25I-NBOH and 2C-I via differential pulse voltammetry: a rapid and sensitive screening method to avoid misidentification

    A. F. Belchior de Andrade and J. Gonzalez-Rodriguez, Analyst, 2019, 144, 2965
    DOI: 10.1039/C9AN00062C

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