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Single Gold Nanoprobe for Colorimetric Detection of Silver (I) Ions with Dark-Field Microscopy

Abstract

Highly sensitive colorimetric detection of silver (I) ions (Ag+) at the single-particle level was developed based on the color of gold nanoparticles (AuNPs) assembly captured by the dark-field microscopy (DFM) imaging. Formation of C-Ag+-C bonding between cytosines was utilized to induce the interparticle coupling of AuNPs modified with single-strand DNA, resulting in a color change as the signal transduction to quantify Ag+ under DFM imaging. This method allowed the visual quantitation of Ag+ in the range of 0.05 nM-250.00 nM and the detection limit of 28.8 pM was achieved. Furthermore, we demonstrated the applicability for the colorimetric detection of Ag+ in a small quantity of real samples, showing the good potential of the developed method in environmental monitoring and drug quality control.

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Publication details

The article was received on 11 Dec 2018, accepted on 10 Jan 2019 and first published on 10 Jan 2019


Article type: Paper
DOI: 10.1039/C8AN02397B
Citation: Analyst, 2019, Accepted Manuscript
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    Single Gold Nanoprobe for Colorimetric Detection of Silver (I) Ions with Dark-Field Microscopy

    Y. F. Xie, Y. Y. Cheng, M. L. Liu, H. Zou and C. Z. Huang, Analyst, 2019, Accepted Manuscript , DOI: 10.1039/C8AN02397B

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