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Issue 4, 2019
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Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

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Abstract

Gold nanoparticles (AuNPs) with unique physical and chemical properties have become an integral part of research in nanoscience. In particular, the development of AuNP-based fluorescent oligonucleotide (AuFO) probes targeted at living systems through fluorescence are drawing increasing attention and have become a current hot topic in biomedical research. This review describes recent advances and developments in the use of AuFO probes from their preparation and features that allow the desired intracellular delivery to their applications in cellular imaging and drug delivery in living systems.

Graphical abstract: Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

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Article information


Submitted
27 Oct 2018
Accepted
12 Dec 2018
First published
13 Dec 2018

Analyst, 2019,144, 1052-1072
Article type
Critical Review

Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems

Y. Yang, S. Zhong, K. Wang and J. Huang, Analyst, 2019, 144, 1052
DOI: 10.1039/C8AN02070A

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