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Issue 1, 2019
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A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids

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Abstract

An enzyme-free and ultrasensitive fluorescence assay for the detection of nucleic acids was successfully established by a hybridization-triggered DNAzyme cascade (HTDC). This simple and cost-effective sensor has good sensitivity, selectivity and the capability for detection of target DNA from complex fluids.

Graphical abstract: A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids

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Publication details

The article was received on 17 Sep 2018, accepted on 22 Oct 2018 and first published on 27 Oct 2018


Article type: Communication
DOI: 10.1039/C8AN01796D
Citation: Analyst, 2019,144, 143-147

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    A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids

    H. Wang, D. He, R. Wu, H. Cheng, W. Ma, J. Huang, H. Bu, X. He and K. Wang, Analyst, 2019, 144, 143
    DOI: 10.1039/C8AN01796D

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