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Issue 42, 2019
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Photoinduced chitosan–PEG hydrogels with long-term antibacterial properties

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Photochemical processes offer the possibility of preparing functional hydrogels under green conditions that are compatible with both synthetic and natural polymers. In this study, chitosan-based poly(ethylene) glycol (PEG) were successfully synthesized under light irradiation in aqueous medium. Kinetic studies under irradiation showed that less than 2 min were necessary to obtain fully cross-linked networks. Thermomechanical analyses and swelling experiments indicated that introduction of chitosan overall weakens the hydrogel network but can create domains of higher thermal stability than the PEG-alone structure. The resulting chitosan–PEG hydrogels demonstrated a tremendous inhibition (100%) of bacterial growth (Escherichia coli and Staphylococcus aureus). After 6 months’ ageing, one of the hydrogels preserved a high antifouling activity against Escherichia coli. This interesting result, which could be correlated with the network features, demonstrates the strong potential of these photochemical methods to obtain robust bio-functional materials.

Graphical abstract: Photoinduced chitosan–PEG hydrogels with long-term antibacterial properties

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Supplementary files

Article information

11 Jun 2019
19 Sep 2019
First published
19 Sep 2019

J. Mater. Chem. B, 2019,7, 6526-6538
Article type

Photoinduced chitosan–PEG hydrogels with long-term antibacterial properties

P. Sautrot-Ba, N. Razza, L. Breloy, S. A. Andaloussi, A. Chiappone, M. Sangermano, C. Hélary, S. Belbekhouche, T. Coradin and D.-L. Versace, J. Mater. Chem. B, 2019, 7, 6526
DOI: 10.1039/C9TB01170F

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