Jump to main content
Jump to site search

Issue 31, 2019
Previous Article Next Article

Stress relaxation in F-actin solutions by severing

Author affiliations

Abstract

Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of actin-associated proteins that control cross-linking, polymerization and force generation in the cytoskeleton. Inspired by recent rheological experiments on reconstituted solutions of dynamic actin filaments, we report a theoretical model that describes stress relaxation behavior of these solutions in the presence of severing proteins. We show that depending on the kinetic rates of assembly, disassembly, and severing, one can observe both length-dependent and length-independent relaxation behavior.

Graphical abstract: Stress relaxation in F-actin solutions by severing

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Jun 2019, accepted on 18 Jul 2019 and first published on 25 Jul 2019


Article type: Paper
DOI: 10.1039/C9SM01263J
Soft Matter, 2019,15, 6300-6307

  •   Request permissions

    Stress relaxation in F-actin solutions by severing

    S. Arzash, P. M. McCall, J. Feng, M. L. Gardel and F. C. MacKintosh, Soft Matter, 2019, 15, 6300
    DOI: 10.1039/C9SM01263J

Search articles by author

Spotlight

Advertisements