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Issue 51, 2019
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Formal synthesis of (+)-lactacystin from l-serine

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Abstract

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-L-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Graphical abstract: Formal synthesis of (+)-lactacystin from l-serine

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Publication details

The article was received on 29 Jul 2019, accepted on 12 Sep 2019 and first published on 24 Sep 2019


Article type: Paper
DOI: 10.1039/C9RA07244F
RSC Adv., 2019,9, 30019-30032
  • Open access: Creative Commons BY license
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    Formal synthesis of (+)-lactacystin from L-serine

    P. C. Bulman Page, R. L. Goodyear, Y. Chan, A. M. Z. Slawin and S. M. Allin, RSC Adv., 2019, 9, 30019
    DOI: 10.1039/C9RA07244F

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