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Issue 1, 2019
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Graphene oxide mediated thiolation of indoles in water: a green and sustainable approach to synthesize 3-sulfenylindoles

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Abstract

An atom economical and transition-metal and iodine free procedure of graphene oxide (a heterogeneous, recyclable, inexpensive, and environment-friendly carbocatalyst) mediated thiolation of indoles, using thiols as a thiolating reagent, has been developed. This methodology provides a catalyst-recyclable and organic-solvent-free protocol to afford 3-sulfenylindoles with good functional group tolerance and broad substrate scope.

Graphical abstract: Graphene oxide mediated thiolation of indoles in water: a green and sustainable approach to synthesize 3-sulfenylindoles

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Article information


Submitted
17 Jul 2018
Accepted
26 Nov 2018
First published
26 Nov 2018

Org. Chem. Front., 2019,6, 116-120
Article type
Research Article

Graphene oxide mediated thiolation of indoles in water: a green and sustainable approach to synthesize 3-sulfenylindoles

M. Chen, Y. Luo, C. Zhang, L. Guo, Q. Wang and Y. Wu, Org. Chem. Front., 2019, 6, 116
DOI: 10.1039/C8QO00726H

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