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Issue 19, 2019
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Synthesis of pyrazolylvinyl ketones from furan derivatives

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Abstract

A new protocol for the synthesis of pyrazol-5-ylvinyl ketones, e.g. pyrazole-chalcones, employing furfuryl ketones as a triketone equivalent, has been developed. The reaction occurs under mild conditions and does not require the use of expensive materials. Other important benefits include the simplicity and atom efficiency of this approach.

Graphical abstract: Synthesis of pyrazolylvinyl ketones from furan derivatives

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Publication details

The article was received on 26 Mar 2019, accepted on 17 Apr 2019 and first published on 18 Apr 2019


Article type: Paper
DOI: 10.1039/C9OB00701F
Org. Biomol. Chem., 2019,17, 4850-4855

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    Synthesis of pyrazolylvinyl ketones from furan derivatives

    N. Sawengngen, P. N. Chalikidi, S. Araby, F. Hampel, P. Gmeiner and O. V. Serdyuk, Org. Biomol. Chem., 2019, 17, 4850
    DOI: 10.1039/C9OB00701F

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