Jump to main content
Jump to site search

Issue 5, 2019
Previous Article Next Article

Pt nanozyme for O2 self-sufficient, tumor-specific oxidative damage and drug resistance reversal

Author affiliations

Abstract

Herein, an ultrathin Pt nanozyme has been developed. The Pt nanozyme exhibited both oxidase and peroxidase-mimetic properties, leading to relieved hypoxia and specific oxidative damage in tumor cells in a cascade manner. Meanwhile, hydrophilic Pt2+ was released sustainably under tumor acidity. These properties endow the Pt nanozyme with great potential in killing drug resistant tumor cells while not damaging normal cells.

Graphical abstract: Pt nanozyme for O2 self-sufficient, tumor-specific oxidative damage and drug resistance reversal

Back to tab navigation

Supplementary files

Publication details

The article was received on 15 Feb 2019, accepted on 11 Apr 2019 and first published on 12 Apr 2019


Article type: Communication
DOI: 10.1039/C9NH00088G
Nanoscale Horiz., 2019,4, 1124-1131

  •   Request permissions

    Pt nanozyme for O2 self-sufficient, tumor-specific oxidative damage and drug resistance reversal

    Z. Ma, L. Wu, K. Han and H. Han, Nanoscale Horiz., 2019, 4, 1124
    DOI: 10.1039/C9NH00088G

Search articles by author

Spotlight

Advertisements