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Issue 6, 2019
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Non-spherical micro- and nanoparticles in nanomedicine

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Abstract

Recent studies have revealed the effects of shape on in vivo nanoparticle circulation, distribution, extravasation, and cellular uptake. Morphology is therefore becoming a key factor to be considered in the rational design of nanoparticulate systems for specific biomedical applications such as targeted drug delivery. Technologies for reliable and scalable fabrication of shape-specific micro- and nanoparticles are emerging, which will allow further investigations into this crucial parameter that is poised to substantially impact nanomedicine.

Graphical abstract: Non-spherical micro- and nanoparticles in nanomedicine

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Article information


Submitted
29 Nov 2018
Accepted
27 Feb 2019
First published
27 Feb 2019

Mater. Horiz., 2019,6, 1094-1121
Article type
Review Article

Non-spherical micro- and nanoparticles in nanomedicine

X. Zhu, C. Vo, M. Taylor and B. R. Smith, Mater. Horiz., 2019, 6, 1094
DOI: 10.1039/C8MH01527A

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